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Home > Products > Pharmaceutical Raw Materials > Propylene glycol

Propylene glycol

Name: Propylene glycol
SKU: 0

CAS No.: 57-55-6
Molecular Formula: C3H8O2
Molecular Weight: 76.09

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product description

Propylene Glycol USP/EP/FCC (CAS 57-55-6) is a high-purity (>99.5%) multi-functional liquid solvent and humectant compliant with global pharmacopeia standards. As a USP-grade pharmaceutical excipient, it serves as low-endotoxin (≤0.5EU/ml) injection solvent; in cosmetics, it acts as OECD 439-certified low-irritant humectant; for food processing, FCC-grade PG functions as antifreeze carrier (21 CFR 184.1666); while industrial applications leverage its low-toxicity antifreeze properties (-59°C, ASTM D1384). Technical documentation available.

Chemical Properties

Property	Value
Melting point	-60 °C (lit.)
Boiling point	187 °C (lit.)
Density	1.036 g/mL at 25 °C (lit.)
Vapor density	2.62 (vs air)
Vapor pressure	0.08 mm Hg ( 20 °C)
Refractive index	n20/D1.432(lit.)
FEMA	2940 \| PROPYLENE GLYCOL
Fp	225 °F
Storage temp.	Store at +5°C to +30°C.
Solubility	Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
Pka	14.49±0.20(Predicted)
Form	Viscous Liquid
Color	APHA: ≤10
Specific Gravity	1.038 (20/20℃)1.036～1.040
PH	6-8 (100g/l, H2O, 20℃)
Odor	at 100.00 %. odorless very slight alcoholic
Odor Type	odorless
Optical Rotation	-0.11° (C=1.00g/100ml, CHCL3)
biological source	synthetic
explosive limit	2.4-17.4%(V)
Water Solubility	miscible
Sensitive	Hygroscopic
Merck	14,7855
JECFA Number	925
BRN	1340498
Dielectric constant	32.0
InChIKey	DNIAPMSPPWPWGF-UHFFFAOYSA-N
LogP	-0.92
Surface tension	35.44mN/m at 298.15K
CAS DataBase Reference	57-55-6(CAS DataBase Reference)
NIST Chemistry Reference	Propylene glycol(57-55-6)
EPA Substance Registry System	Propylene glycol (57-55-6)

Safety Information

Property	Value
Safety Statements	24/25
WGK Germany	1
RTECS	TY2000000
Autoignition Temperature	779 °F
TSCA	Yes
HS Code	29053200
Hazardous Substances Data	57-55-6(Hazardous Substances Data)
Toxicity	LD50 orally in Rabbit: 19400 - 36000 mg/kg LD50 dermal Rabbit 20800 mg/kg

Product Usage

Propylene glycol is a versatile, colorless, and odorless liquid widely utilized for its excellent solvent, humectant, and preservative properties. In the food and beverage industry, it serves as a safe carrier for flavors and colors, and as a humectant to maintain moisture in baked goods and dairy products. Its role in cosmetics and personal care is equally vital, acting as a moisture-retaining agent in lotions, shampoos, and toothpastes to ensure smooth application and skin hydration. In the pharmaceutical sector, it is used as a solvent for injectable and oral medications to enhance stability and absorption. Additionally, it has significant industrial applications, notably as a non-toxic antifreeze and heat-transfer fluid in HVAC systems, as well as a key raw material for manufacturing high-performance unsaturated polyester resins.

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FAQ

Q1：Does it support customized products?

A1：Yes, it does. Formulations can be adjusted and customized production can be carried out according to customer's industry needs and performance parameters.

Q2：Can samples be provided?

A2：We support free sample delivery and testing services to meet customers' early testing needs.

Q3：Is the product quality stable?

A3：With full-process quality inspection and control, there are minimal batch differences, and the purity and stability strictly meet the standards.

Q4：What is the shipping cycle?

A4：For regular inventory, we offer quick delivery. For customized orders, we arrange production according to demand and ensure timely delivery.

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