(-)-Epigallocatechin gallate

(-)-Epigallocatechin gallate

CAS No.: 989-51-5
Molecular Formula: C22H18O11
Molecular Weight: 458.37
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product description
(-)-epigallocatechin 3-gallate is a gallate ester obtained by the formal condensation of gallic acid with the (3R)-hydroxy group of (-)-epigallocatechin.  It has a role as an antineoplastic agent, an antioxidant, a Hsp90 inhibitor, a neuroprotective agent, a plant metabolite, a geroprotector and an apoptosis inducer.  It is a gallate ester, a polyphenol and a member of flavans.  It is functionally related to a (-)-epigallocatechin.


Chemical Properties
PropertyValue

Melting point

222-224°C

Alpha

D -185 ±2°(ethanol)

Refractive index

-175.5 ° (C=1, EtOH)

Storage temp.

2-8°C

Solubility

H2O: ≥5mg/mL, clear

Form

Solid

Boiling point

909.1±65.0 °C(Predicted)

Density

1.90±0.1 g/cm3(Predicted)

PKa

7.75±0.25(Predicted)

Color

White to Light Brown

Biological source

Green tea

Water Solubility

Soluble in ethanol, dimethyl formamide, water.

Merck

14,3526

Stability

Stable, but may be light sensitive. Incompatible with strong oxidizing agents.

InChIKey

WMBWREPUVVBILR-WIYYLYMNSA-N

LogP

0.639 (est)

CAS DataBase Reference

989-51-5(CAS DataBase Reference)


Safety Information

PropertyValue

Safety Statements

24/25

WGK Germany

2

RTECS

KB5200000

F

10-23

HS Code

29339900

Toxicity

LD50 oral in mouse: 2170mg/kg


Product Usage

(-)-Epigallocatechin gallate (EGCG), the most abundant and potent catechin found in green tea, is a world-renowned antioxidant widely utilized in the nutraceutical and functional food industries. It is a primary active ingredient in dietary supplements aimed at weight management, metabolic support, and cardiovascular protection. In the cosmetic and dermo-pharmaceutical sector, EGCG is highly prized for its anti-inflammatory and photoprotective properties, often incorporated into high-end skincare formulations to prevent UV-induced damage and slow the signs of aging. Beyond consumer goods, it plays a vital role in biomedical research, where it is studied for its potential in cancer prevention and its ability to inhibit protein misfolding in neurodegenerative diseases. Additionally, its natural antimicrobial properties make it an effective food preservative, helping to extend shelf life and maintain the nutritional integrity of processed oils and fats.

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FAQ

Q1:Does it support customized products?

A1:Yes, it does. Formulations can be adjusted and customized production can be carried out according to customer's industry needs and performance parameters.


Q2:Can samples be provided?

A2:We support free sample delivery and testing services to meet customers' early testing needs.


Q3:Is the product quality stable? 

A3:With full-process quality inspection and control, there are minimal batch differences, and the purity and stability strictly meet the standards.


Q4:What is the shipping cycle?

A4:For regular inventory, we offer quick delivery. For customized orders, we arrange production according to demand and ensure timely delivery.

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